The WHS club was still firing down the stretch in the final quarter, outscoring E-LC 18-12, after falliung back at halftime by a 35-15 margin, and trailing 52-26 heading into the fourth frame.
Shanon Shaefer led Cherokee scoring with 10 points, followed by Megan Hummel nine, Megan Carlson seven, and Jackie Wilson and Taylor Woods six apiece.
Cherokee sank 15-43 field goals for 35 percent, including 5-19 three-balls, and a 9-14 effort from the foul line. E-LC was 11-16 from the free throw line.
Shaefer led Cherokee in assists with four, Wilson tallied three blocked shots, and Carlson, Shaefer and Hummel had three steals apiece.
"We laid an egg in the first quarter," said Cherokee coach Heath Hagberg. "We were a little bit in awe of their reputation of holding Spencer to just 10 points and Storm Lake to five, But our girls figured it out and played hard the rest of the way and we played them even. We settled down and played consistent basketball and we played hard as they always do."
Hagberg creditied Woods with a solid second half, saying she is getting her confidence back after battling health issues and is returning to form.
"Shanon took the ball to the basket and megan carlson and Megan Hummel settled down and produced after that early deficit. It was just too big of a hole against such a quality team.
The 1-6 Cherokee girls now enter the holiday break after playing five ranked teams in their first seven games.