Cherokee blew to a 34-11 halftime lead and then played it cozy in the second half, with the Tornadoes draining three-pointers to keep it close before the 21-point victory was well in hand.
Megan Hummel paced Cherokee with 13 points, followed by Shanon Shaefer 10, and Megan Carlson eight. Chyann Smith led Storm Lake's scoring with 14 points, and Brenna Richter added 11.
Hummel also paced the WHS girls in steals with eight, and Jackie Wilson had six.
"We did a lot of experimenting in the game," noted Cherokee coach Heath Hagberg. "We played man-to-man defense in the third quarter and we had not done that this year, so the girls were trying it on the fly.
"We got everybody in the game, so that was nice. Shanon and the two Megans (Carlson, Hummel) had good games for us and played solid basketball."
Cherokee (2-7) hosts #1 Odebolt-Arthur/Battle Creek-Ida Grove (11-0) tonight.